Chapter 1 Introduction

1.1 The Function and Elements of Pathophysiology

1.2 The Major Research Methods Involved in Pathophysiology

Chapter 2 Concept of Disease

2.1 Concepts of Health and Disease

2.2 Etiology

2.3 Pathogenesis

2.4 Clinical Manifestations

2.5 Diagnosis

2.6 Clinical Course

2.7 0utcome of Disease

Chapter 3 Water and Electrolyte Metabolism

3.1 Water and Sodium Metabolism Disorders

3.2 Disorders of Potassium Metabolism

Chapter4 Acid-base Disturbance

4.1 The Regulation of Acid-base Homeostasis

4.2 Simple Acid-base Disorders

4.3 Complex Acid-base Disorders

4.4 Clinical Measurements and Analysis of Acid-base Disorders

Chapter 5 Stress

5.1 Stressor

5.2 Stress Response

5.3 Altered Metabolism and Function

5.4 Stress Diseases and Stress Related Diseases

5.5 Pathophysiological Basis of Prevention and Treatment for Stress Disorders

Chapter 6 Fever

6.1 Etiology

6.2 Stages and Manifestation

6.3 Altered Metabolism and Function .

6.4 Pathophysiological Basis of Prevention and Treatment

Chapter 7 Hypoxia，

7.2 Classification, Etiology and Mechanisms of Hypoxia

7.3 Alterations of Metabolism and Function in the Body

7.4 Pathophysiological Basis of Prevention and Treatment of Hypoxia

Chapter 8 Disorders of Balance between Coagulation and Anticoagulation

8.1 Normal Balance between Coagulation and Anticoagulation

8.2 Disseminated Intravascular Coagulation (DIC)

Chapter 9 Ischemia-reperfusion Injury

9.1 Etiology

9.2 Duration of lschemia

9.4 Alterations of Metabolism and Function in Myocardial Ischemia-reperfusion Injury

9.7 Pathophysiological Basis of Prevention and Treatment

Chapter 10 Shock

10.1 The Etiology and Classification of Shock

10.2 The Development Process and Underlying Mechanisms of Shock

10.3 Cell Injury and Metabolic Changes in Shock

10.4 0rgan Dysfunction during Shock

10.5 Treatment of Shock andlts Rationale

Chapter 11 Heart Failure

11.1 Etiology of Cardiac Insuffiaency

11.3 CompensatoryResponsesinCardiaclnsufficiency

11.5 Alterations of Metabolism and Function in Cardiac Insufficiency

11.6 Pathophysiological Basis of Prevention and Treatment for Cardiac Insufficiency

Chapter 12 Respiratory Failure

12.1 The Etiology and Pathogenesis

12.2 The Alteration of Function and Metabolism

12.3 The Pathophysiological Basis of Treatment

Chapter 13 Hepatic Insufficiency

13.1 Hepatic Insufficiency

13.2 Hepatic Encephalopathy

13.3 Hepatorenal Syndrome

Chapter 14 Renal Failure

14.1 Etiology and Pathogenesis of Acute Renal Failure

14.2 Alterations of Metabolism/Function during ARF

14.3 Acute Renal Failure Management