内分泌系统（第2版） / 以器官为中心原版教材
作者： Joy Hinson
出版时间：2011年6月
出版社：北京大学医学出版社
- 北京大学医学出版社
- 9787565901157
- 195019
- 0049153139-8
- 平装
- 16开
- 2011年6月
- 医学
- 临床医学
- R335
- 医学
- 研究生、本科
“以器官系统为中心”的医学教学模式是国际医学教育的趋势。本系列书是世界著名医药卫生出版集团爱思唯尔公司出版的一套“以器官系统为中心”的医学基础课程教材。该套教材第1版出版后受到世界各地许多医学院校的欢迎，并被多家进行“以器官系统为中心”教学的医学院校选定为教材。第2版根据第1版出版后教师和学生的反馈意见，结合医学知识的更新进行了全新修订。在编写内容上，该系列教材强调基础与临床的整合。每一章节都是围绕着一个临床病例展开，通过对病人问题的呈现以及解决过程引出对相关知识的探究，从而使与器官系统结构、功能以及疾病相关的重要的基础医学知识得到了完善的整合。在版式安排上，图框中的病例资料与正文中的医学知识完美匹配，一步一步地激起读者的求知欲望。本册为《内分泌系统》。
1 INTRODUCTION 1
What is endocrinology? 2
What do hormones do? 2
Types of hormone: their synthesis and secretion 4
The transport and metabolism of hormones 7
Important concepts in endocrine regulation 8
Endocrine disorders 10
Endocrine investigations: general principles 12
2 RECEPTORS AND HORMONE ACTION 15
Introduction 16
General characteristics of receptors 16
Types of hormone receptors 17
Cell-membrane receptors 17
Hormonal regulation of transcription 23
Intracellular receptors 24
Disorders of receptor function 26
3 THE HYPOTHALAMUS AND PITUITARY PART I: THE HYPOTHALAMUS AND POSTERIOR PITUITARY 27
Introduction 28
Where can I find the hypothalamus and pituitary? 28
Connection between the hypothalamus and pituitary 31
Development of the hypothalamus and pituitary 31
The hormones of the hypothalamus 31
The hormones of the posterior pituitary 32
Release of posterior pituitary hormones is part of a neuroendocrine reflex: oxytocin secretion and actions 32
Regulation of vasopressin secretion 33
Actions of arginine vasopressin 34
Disorders of vasopressin secretion and action 35
Thirst 36
Other hypothalamic hormones 37
4 THE HYPOTHALAMUS AND PITUITARY PART II: THE ANTERIOR PITUITARY 39
Introduction 40
Structure of the anterior pituitary 40
The hormones of the anterior pituitary 41
Regulation of hormone secretion in the anterior pituitary 43
Growth hormone and prolactin in blood 46
Actions of the anterior pituitary hormones growth:
hormone and prolactin 46
Disorders of anterior pituitary function:
over-secretion 48
Disorders of under-secretion of anterior pituitary
hormones 49
Tests for hypopituitarism 50
Insufficient growth hormone secretion 50
5 THE ADRENAL GLANDS PART I: THE ADRENAL MEDULLA 53
Introduction 54
Where to find the adrenal glands 54
Blood supply 54
Nerve supply 55
Embryology of the adrenal gland 55
The adrenal medulla 55
Disorders of the adrenal medulla: phaeochromocytorna 59
Familial phaeochromocytoma 59
Pharmacological uses of hormones of the adrenal medulla 60
6 THE ADRENAL GLANDS PART II: THE ADRENAL CORTEX 61
Introduction 62
Structure of the adrenal cortex 62
Hormones produced by the adrenal
cortex 62
Regulation of steroid production 66
Transport of steroid hormones in blood 68
Disorders of adrenal steroids 71
Pharmacological use of glucocorticoids 73
7 THE THYROID GLAND 75
Introduction 76
Thyroid anatomy 77
What is a goitre? 77
Blood supply 77
Structure of the thyroid 78
Synthesis of thyroid hormones 78
Iodine 79
Thyroxine and T3: the thyroid hormones in blood 79
Control of thyroid function 81
Cellular action of thyroid hormones 82
Effects of thyroid hormones 82
Disorders of thyroid hormone secretion 83
Causes of thyroid hyposecretion 85
Effects of thyroid hormone insufficiency: myxoedema 85
8 HORMONAL CONTROL OF REPRODUCTION PART I: MALE REPRODUCTIVE SYSTEM 87
Introduction 88
Where are the testes? 88
What are the testes? 89
Testicular blood and nerve supply 90
Spermatogenesis 91
Androgen production 91
Hormonal control of testicular function 91
Transport of testosterone in blood 93
Actions of testosterone 93
Hormone-dependent cancer in men 95
Disorders of male reproduction 96
Therapeutic uses of androgens 97
Abuse of anabolic androgenic steroids 97
Declining sperm counts 98
9 HORMONAL CONTROL OF REPRODUCTION PART II: FEMALE REPRODUCTIVE SYSTEM 99
Introduction 100
Structure of the ovary 100
Ovarian hormones 100
Transport and metabolism of oestrogen and
progesterone 102
Oestrogens 102
Androgen secretion by,the ovaries 104
Hormonal regulation of ovarian function 105
Hormone-dependent cancer in women 105
The menstrual cycle 105
Disorders of the menstrual cycle 108
The endocrinology of pregnancy 110
10 HORMONAL CONTRO
