Preface

Acknowledgments

1. CELLULAR REACTION TO INJURY

  I. Adaptation to Environmental Stress

  II. Hypoxic Cell Injury

  III. Free Radical Injury

  IV. Chemical Cell Injury

  V. Necrosis

  VI. Apoptosis

  VII. Reversible Cellular Changes and Accumulations

  VIII. Disorders Characterized by Abnormalities of Protein Folding

  Review Test

2. INFLAMMATION

  I. Introduction

  II. Acute Inflammation

  III. Chronic Inflammation

  IV. Tissue Repair

  Review Test

3. HEMODYNAMIC DYSFUNCTION

  I. Hemorrhage

  II. Hyperemia

  III. Infarction

  IV. Thrombosis

  V. Embolism

  VI. Edema

  VII. Shock

  Review Test

4.  GENETIC DISORDERS

  I. Chromosomal Disorders

  II. Modes of Inheritance of Monogenic Disorders

  III. Mendelian Disorders

  IV. Balanced Polymorphism

  V. Polygenic and Multifactorial Disorders

  VI. Disorders of Sexual Differentiation

  Review Test

5. IMMUNE DYSFUNCTION

  I. Cells of the Immune System

  II. Cytokines

  III. Complement System

  IV. Human Leukocyte Antigen System

  V. Innate versus Acquired Immunity

  VI. Mechanisms of Immune Injury

  VII. Transplantation Immunology

  VIII. Immunodeficiency Diseases

  IX. Autoimmunity

  X. Connective Tissue (Collagen) Diseases

  XI. Amyloidosis

  Review Test

6. NEOPLASIA

  I. General Considerations

  II. Classification and Nomenclature of Tumors

  III. Properties of Neoplasms

  IV. Carcinogenesis and Etiology

  V. Other Neoplastic Disorders with Known DNA Defects

  VI. Grading and Staging

  Review Test

7. ENVIRONMENTAL PATHOLOGY

  I. Physical Injury

  II. Chemical Abuse

  III. Environmental Chemical Injuries

  IV. Adverse Effects of Therapeutic Drugs

  Review Test

8. NUTRITIONAL DISORDERS

  I. Malnutrition

  II. Vitamins

  III. Obesity

  Review Test

9. VASCULAR SYSTEM

  I. Arterial Disorders

  II. Venous Disorders

  III. Tumors of Blood Vessels

  IV. Vasculitis Syndromes (Vasculitides)

  V. FunctionalVascularDisorders

  VI. Hypertension

  Review Test

10. THE HEART

  I. lschemic Heart Disease (IHD)

  II. Rheumatic Fever

  III. Other Forms of Endocarditis

  IV. Valvular Heart Disease

  V. Congenital Heart Disease

  VI. Diseases of the Myocardium

  VII. Diseases of the Pericardium

  VIII. Tumors of the Heart

  IX. Congestive Heart Failure

  X. Hypertrophy of the Heart

  Review Test

11. ANEMIA

  I. GeneralConcepts

  II. Acute Posthemorrhagic Anemia

  III. Iron Deficiency Anemia

  IV. Megaloblastic Anemias

  V. Anemia of Chronic Disease

  VI. Aplastic Anemia

  VII. Myelophthisic Anemia

  VIII. Hemolytic Anemias

  Review Test

12. NEOPLASTIC AND PROLIFERATIVE DISORDERS

    OF THE HEMATOPOIETIC AND LYMPHOID SYSTEMS

  I. Leukemia

  II. Myeloproliferative Diseases

  III. Non-Neoplastic Lymphoid Proliferations

  IV. Plasma Cell Disorders

  V. Lymphoid Neoplasms

  Review Test

13. HEMORRHAGIC DISORDERS

  I. Disorders of Primary Hemostasis

  II. Disorders of Secondary Hemostasis

  III. Combined Primary and Secondary Hemostatic Defects

  Review Test

14. RESPIRATORY SYSTEM

  I. Disorders of the Upper Respiratory Tract

  II. Tumors of the Upper Respiratory Tract

  III. Chronic Obstructive Pulmonary Disease (COPD)

  IV. Restrictive Pulmonary Disease

  V. PulmonaryVascular Disease

  VI. Pulmonary Infection

  VII. Miscellaneous Disorders of the Lungs

  VIII. Cancers of the Lung

  Review Test

15. GASTROINTESTINAL TRACT

  I. Diseases of the Mouth and Jaw

  II. Diseases of the Salivary Glands

  III. Diseases of the Esophagus

  IV. Diseases of the Stomach

  V. Diseases of the Small Intestine

  VI. Diseases of the Colon

  VII. Diseases of the Appendix

  Review Test

16. LIVER, GALLBLADDER, AND EXOCRINE PANCREAS

  I. Diseases of the Liver

  II. Diseases of the Gallbladder

  III. Diseases of the Exocrine Pancreas

  Review Test

17. KIDNEY AND URINARY TRACT

  I. Congenital Anomalies of the Urinary Tract

  II. Glomerular Diseases

  III. Urinary Tract Obstruction

  IV. Infe